Our Research
Cells rely on complex signaling receptors to interpret environmental cues and make critical decisions about growth, survival, and differentiation. In my lab, we are engineering synthetic, small molecule-inducible signaling receptors that allow precise, programmable control over these cellular decisions. Using
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α-Thalassemia is a severe genetic blood disorder caused by the loss of genes required to produce hemoglobin, the protein in red blood cells that carries oxygen throughout the body. In this study, we used precision genome editing to insert a
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CRISPR genome editing is transforming medicine, but ensuring its safety is just as important as demonstrating its power. In my lab, we rigorously evaluate how often CRISPR makes unintended DNA changes and tested the most advanced methods available to detect
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